We present surface maps based on BVRI photometry obtained at Perkins However, symptomatic brain metastases are associated with dismal prognosis, so early detection and treatment could be advisable. In a survey, we investigated the influence of COVID-19 on the care of NET patients in the German speaking countries Germany, Austria and Switzerland. However, some reports also described a correlation to carcinoid tumors, probably triggered via the excessive release of hormones. Katharina Theuerkorn's 8 research works with 8 citations and 288 reads, including: Correction: Interaction between somatostatin analogues and targeted therapies in neuroendocrine tumor cells Both available depot formulations of SSA, long-acting repeatable (LAR) octreotide and lanreotide autogel, seem similarly effective and well tol... Background: wir, das Universitätsklinikum Halle (Saale), führen im Moment eine Umfrage über die Nutzung unserer Internetseite durch. K8 main sequence star known to exhibit large cool spots on its surface. Pancreatic ductal adenocarcinoma (PDAC) is associated with poor prognosis. Sebastian Kruger’s works are appreciated and collected by many Hollywood notables, and his painterly twists on Bogart, Schwarzenegger John Wayne, The Rolling Stones, are classics of their kind. - Artista tedesco (n. Hameln 1963). We report the case of a 40-year-old woman that was diagnosed with a neuroen... Einleitung: Die Standardbehandlung fur gut-differenzierte metastasierte neuroendokrine Neoplasien des Pankreas (PNEN) ist die Chemotherapie mit Streptozotocin (STZ) und 5-FU oder Doxorubicin (Doc). After ruling out malignant and infectious causes, positron emission tomography-computed tomography (PET-CT) revealed markedly elevated glucose utilization of the large thoracic and upper limb arteries, suggesting systemic vasculitis. Invitations to participate in a... Background: Systemische Therapien bei neuroendokrinen Neoplasien des Pankreas, Impact of intensified chemotherapy in metastatic pancreatic ductal adenocarcinoma (PDAC) in clinical routine in Europe, Charakterisierung von epigenetischen Modulatoren in pankreatischen Neuroendokrinen Tumorzellen, Identifying prognostic factors for well-differentiated metastatic pancreatic neuroendocrine tumours (pNETs): A retrospective international multicenter cohort study, Therapie adenoneuroendokriner Mischtumoren des Gastrointestinaltrakts, Therapeutic Targeting of Tumor-Associated Macrophages in Pancreatic Neuroendocrine Tumors: TAMs mediate tumor progression in PNET, Clinicopathological hallmarks and biomarkers of colorectal neuroendocrine neoplasms, Overcoming immune evasion in pancreatic cancer: the combination matters, Metabolische Entgleisungen als paraneoplastische Syndrome, Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis, The Role of Cytotoxic Chemotherapy in Advanced Pancreatic Neuroendocrine Tumors, Characterization of IGF2BP proteins in pancreatic neuroendocrine neoplasms, Impact of Intensified Chemotherapy in Metastatic Pancreatic Ductal Adenocarcinoma (PDAC) in Clinical Routine - A European retrospective multicenter study. Impact of Therapy Sequence with Alkylating Agents and MGMT Status in Patients with Advanced Neuroendocrine Tumors, Esophageal Cancer: New Insights into a Heterogenous Disease, Real-World Clinical Practice of Intensified Chemotherapies for Metastatic Pancreatic Cancer: Results from a Pan-European Questionnaire Study, Relevance of dihydropyrimidine-dehydrogenase and thymidylate-synthase in patients with pancreatic neuroendocrine neoplasms treated with 5-FU-based chemotherapy, Intensified chemotherapy for metastatic pancreatic cancer: interim analysis of a large retrospective pan-European database and real life evaluation, Der Einfluss von Lanreotid und molekular zielgerichteten Therapien auf die SSTR Expression und die Zellüberlebensfähigkeit in neuroendokrinen Tumorzelllinien, Analyse prognostisch relevanter Faktoren bei fortgeschrittenen neuroendokrinen Tumoren des Pankreas, Effekte des antiangiogenen Multityrosinkinase-Inhibitors Regorafenib auf infiltrierende Makrophagen in pankreatischen neuroendokrinen Tumoren, Low dose DTIC is effective and safe in pretreated patients with well differentiated neuroendocrine tumors, Acromegaly in a patient with a pulmonary neuroendocrine tumor: Case report and review of current literature, A Pan-European study to evaluate the impact of intensified chemotherapy in metastatic pancreatic ductal adenocarcinoma (PDAC) in clinical routine, Non-tumour cell autonomous effects of antiangiogenic multikinase inhibitor regorafenib on infiltrating macrophages in pancreatic neuroendocrine tumours, Use of intensified chemotherapy for metastatic pancreatic cancer in Europe – Results from a Pan-European questionnaire study, miRNA dynamics in tumor-infiltrating myeloid cells modulating tumor progression in pancreatic cancer, A univariate analysis of factors influencing survival in advanced pancreatic neuroendocrine tumors, Evaluation of the therapeutic approaches impacting on the survival of patients with an advanced pancreatic neuroendocrine tumor, Streptozocin-Based Chemotherapy in Patients with Advanced Neuroendocrine Neoplasms - Predictive and Prognostic Markers for Treatment Stratification, Neuroendocrine tumours – Medical therapy: Biological, New Advances in the Treatment of Metastatic Pancreatic Cancer, Charakterisierung der miRNA Dynamik in infiltrierenden Makrophagen während der Tumorprogression des Pankreaskarzinoms, Duale Effekte von Regorafenib auf pankreatische neuroendokrine Tumorzelllinien und Makrophagen, Pharmakologische Depletion von Makrophagen in pankreatischen neuroendokrinen Neoplasien, CUX1 moduliert das Ansprechen auf eine konventionelle Chemotherapie bei Patienten mit metastasierten pankreatischen neuroendokrinen Neoplasien, Impact of pharmacological macrophage depletion on the progression of pancreatic neuroendocrine neoplasms, Acquired 5-Fluorouracil Resistance in Human Pancreatic Carcinoma Cells - A Paradigm for Chemoresistance Mechanisms In Pancreatic Cancer, The Impact of Pharmacological-Mediated Depletion of Macrophages in Pancreatic Neuroendocrine Neoplasms, CUX1: A modulator of tumour aggressiveness in pancreatic neuroendocrine neoplasms, Paraneoplastic brainstem encephalitis in a patient with exceptionally long course of a metastasized neuroendocrine rectum neoplasm, 5-FU-basierte Chemotherapie in neuroendokrinen Neoplasien des Pankreas: prädiktive und prognostische Marker für Therapieansprechen und Überleben, Chromogranin A als diagnostischer Marker und im follow up von Patienten mit neuriendocrinen Neoplasien des Colons und des Rektums, Hirnmetastasen bei Patienten mit Neuroendokriner Neoplasie: Häufigkeit und Prognose, 5-FU-Based Chemotherapy in Pancreatic Neuroendocrine Neoplasms: Predictive and Prognostic Markers for Treatment and Survival, Streptozotocin-Based Chemotherapy is Still Alive in Patients with Neuroendocrine Neoplasms: Predictive and Prognostic Markers for Treatment and Survival, 59-jähriger Patient mit rezidivierendem Erröten bei blander Leberzyste, [A 59-year-old patient with recurrent flushes and bland hepatic cyst. The tumor suppressor Pdcd4 is involved in multiple pathways. SOLD LISTINGS FOR Sebastian Kruger "Good Clint Eastwood 28x45" Limited Edition Print: From the Edition of 99 I have one and want to sell it SOLD "Jagger" Limited Edition Print: Giclee I have one and want to sell it SOLD "Jimi Hendrix Ap 2006" Limited Edition Print: Giclee on Canvas I … However, in unconscious patients special care is needed to detect – possibly life threatening - complications. Uber pradiktive und prognostische Marker in dieser Patientengruppe ist bislang wenig bekannt. The optimal treatment sequence... Background: This study aims to analyze the real-world clinical practice with FOLFIRINOX and gemcitabine + nab-paclitaxel across Europe. University students and faculty, institute members, and independent researchers, Technology or product developers, R&D specialists, and government or NGO employees in scientific roles, Health care professionals, including clinical researchers, Journalists, citizen scientists, or anyone interested in reading and discovering research. Prevented from simply buying a Disney comic book by his parents, Krϋger would study and memorise images of the character, then quickly run home to draw it, going back to the shop if he b… The treatment and monitoring of patients with neuroendocrine tumors (NET) has been a major challenge during the COVID-19 pandemic. Ziel: Charakterisierung von klinisch-pathologischen Patien... Ein 59-jähriger Patient wurde mit rezidivierender Flush-Symptomatik und pathologisch erhöhter 5-Hydroxyindolessigsäure im Sammelurin eingewiesen. Cytotoxic chemotherapy, along with alkylating agents and antimetabolites as well as mole... e15774 Pancreatic neuroendocrine tumors (PNETs) are rare neoplasms accounting for less than 5% of all pancreatic malignancies. In this situation, guidelines for health care professionals in endoscopy units with increased risk of infection from inhalation of airborne droplets, conjunctival contact and faeces are urgently needed. Krüger, Sebastian. Pdcd4 levels are reduced in various tumours and during malignant transformation. Alcohol-related pancreatitis is associated with a disproportionately large number of hospitalisations among GI disorders. In addition, SSA exert significant anti-proliferative effects in mid-gut and pancreatic NET (PanNET). Lists. The House of Tomorrow (2017) cast and crew credits, including actors, actresses, directors, writers and more. Despite its clinical importance, genetic susceptibility to alcoholic chronic pancreatitis (CP) is poorly characterised. Neben den führenden Symptomen Schmerz, Ikterus und Gewichtsverlust können sow... Einleitung: Streptozotozin-basierte Chemotherapien bei Patienten mit metastasierten Pankreas-NETs zeigen ermutigende Ergebnisse, diese Therapie besteht aber aus einem 5-Tage Zyklus und kann zu Niereninsuffizienz fuhren. Recently, it has been shown that plasma levels of CgA correlate with tumor load and predict survival of patients with NEN of the small bowel. Marita Koch Meier (Wismar, 18 febbraio 1957) è un'ex velocista tedesco orientale, campionessa olimpica dei 400 metri piani a Mosca 1980.. Durante la propria carriera ha raccolto un notevole numero di record mondiali: 16 all'aperto, così come 14 negli eventi indoor; è … Furthermore, high amounts of Pdcd4 showed the potential to repress malignant transformation. Many sporadic non-functioning pNET patients are already metastatic at the time of diagnosis, and the therapeutic approach to such patients is mostly palliative. 18. Authors. 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A nationwide survey, Eine abszessverdächtige Raumforderung in der extraokulären AugenmuskulaturSuspected abscess formation in the inferior rectus muscle, Correction: Interaction between somatostatin analogues and targeted therapies in neuroendocrine tumor cells, Brain metastases in patients with neuroendocrine neoplasms: Risk factors and outcome, The nasogastric tube is stuck - and causes coughing and dyspnoea: A rare complication, Charakterisierung von epigenetischen Modulatoren in pankreatischen Neuroendokrinen Neoplasien, DEGUM-CEUS-HCC-Studie zur Kontrastmittelsonografie in der nicht-invasiven Diagnostik des hepatozellulären Karzinoms bei Risikopatienten – eine prospektive, multizentrische Studie, Interaction between somatostatin analogues and targeted therapies in neuroendocrine tumor cells. 23.5k Followers, 50 Following, 1,221 Posts - See Instagram photos and videos from Sebastian Krüger (@sebastiankrugerofficial) This study aims to evaluate the efficacy and safety of the anti-programmed death ligand-1 (PD-... Background After studying free painting with Prof. Dörfler at the Braunschweig University of Fine Arts he made a stunning reputation as the designer of a number of cover spreads for the press in Germany and abroad and as an illustrator and creative designer of various LP covers. However, predictive markers for patient selection are still missing. Here we... Somatostatin analogues (SSA) represent the standard of care for symptom control in patients with functional gastro-entero-pancreatic neuroendocrine tumors (GEP-NET). Jens Werner (München), Sebastian Krug (Halle/ Saale) 08:30–08:38 C-reactive protein (CRP) is associated with poor prognosis by promoting growth signaling pathway activation in pancreatic neuroendocrine neoplasms Case presentation Lists. PD Dr. med. Case presentation Observatory from May-July 2011 and inverted with an algorithm which wir, das Universitätsklinikum Halle (Saale), führen im Moment eine Umfrage über die Nutzung unserer Internetseite durch. In these tumors, paraneoplastic syndromes have been described to drive the course of the disease, among them acromegaly induced by paraneoplastic secretion of growth hormone-releasing hormone (GHRH). However, data about biomarkers involved in the 5-FU metabolism to predict response are still limited. They combine a neuroendocrine component, usually a poorly differentiated neuroendocrine carcinoma, with a nonneuroendocrine part consisting mostly of an adenocarcinoma component. Mit den Ergebnissen dieser völlig anonymen und freiwilligen Umfrage wollen wir unsere Seite für Sie attraktiver und besser nutzbar machen. Recently, FOLFIRINOX and gemcitabine + nab-paclitaxel have been introduced as a novel intensified chemotherapy regimen for patients with metastasized pancreatic cancer. Manuscripts / Autographs. Paraneoplastische Syndrome sind charakterisiert durch die tumorinduzierte Freisetzung von Peptidhormonen und/oder die Induktion von Immunphänomenen, die von der Tumormasse völlig unabhängige klinische und laborchemische Veränderungen hervorrufen. Worldwide, squamous cell carcinomas (SCCs) continue to be the most prevalent subtype; however, in the Western countries, the incidence of adenocarcinomas is increasing and will exceed that of SCC in the near future. med. 48, 7244-7250 (2009) 17. Martin Luther University Halle-Wittenberg, Klinik für Innere Medizin - Gastroenterologie, Endokrinologie und Stoffwechsel (Marburg), Translational Genomics Research Institute, Hospital Universitario Central de Asturias, Are German endoscopy units prepared for the COVID-19 pandemic? Sebastian Krug, Martin-Luther Universität Halle/Wittenberg, Germany Arutha Kulasinghe, Queensland University of Technology, Australia Dhruv Kumar, Amity Institute of Molecular Medicine & Stem Cell Research, Amity University Noida, India Rahul Kumer, Iriving Medical Center, Columbia University, USA Objective Nasogastric tubes are commonly used for transient enteral nutrition and are generally considered safe to use and handle. Clouds. Pulmonary neuroendocrine tumors (NET) form a heterogeneous group of rare diseases. However, symptomatic brain metastases are associated with dismal prognosis, so early detection and treatment could be advisable. Per definition, both tumor parts account for at le... Pancreatic neuroendocrine tumors (PNETs) represent a heterogeneous group of neuroendocrine neoplasms with varying biological behaviour and response to treatment. The young solar analog LO Pegasi is a rapidly rotating (P ≈ 10.2 hr) Iscriviti a Facebook per connetterti con Sebastian Günther e altre persone che potresti conoscere. In this situation, guidelines for health care professionals in endoscopy units with increased risk of infection from inhalation of airborne droplets, conjunctival contact and faeces are urgently needed. Organizzazione insieme a Sebastian Luft (Marquette University, USA) It is assumed that this is as well valid for NEN of th... Hindgut-NEN-data set. Erfahren Sie mehr über die Kontakte von Sebastian Krug und über Jobs bei ähnlichen Unternehmen. Brain metastases (BM) are rarely reported in patients with neuroendocrine carcinoma (NEC) of non-lung origin and neuroendocrine tumors (NET) of the gastroenteropancreatic (GEP) or bronchopulmonary system. Gemcitabine is the standard chemotherapy for patients with metastatic pancreatic adenocarcinoma (MPA). Considering its biological action conflicting data in the literature exist and, consequently, our own studies point to a cell type specific action of Pdcd4. Studierenden-Service-Center. Sebastian KRUG, Medical Doctor of Martin Luther University Halle-Wittenberg, Halle (Saale) (MLU) | Read 80 publications | Contact Sebastian KRUG Eine seit Jahren bekannte und als bland eingestufte Leberzyste konnte als Metastase einer neuroendokrinen Neoplasie des Ileums identifiziert werden. In zwei aufeinanderfolgenden Operationen wurde sowohl d... A 59-year-old patient was admitted to hospital with recurrent flush symptoms and pathologically elevated 5-hydroxyindoleacetic acid (5-HIAA) levels in urine. Background: High grade Neuroendocrine Neoplasias (NEN) are rare tumors with a poor prognosis and no established second line therapy when progressive after first line platinum-based chemotherapy resulting in a median overall survival (OS) of 5 months. To identify kinases whose inhibition acts synergistically with erlotinib, we employed a kinome-wid... Das Adenokarzinom des Pankreas bietet je nach Lokalisation und Ausbreitung ein unterschiedliches klinisches Beschwerdebild. So far, the effects of Pdcd4 seemed to be cell type specific. Infiltrating myeloid cells have been identified not only in invasive tumors, but also in early pre-invasive pancreatic intraepithelial precursor lesio... Background and aim: Background: Gemcitabine (GEM) based chemotherapy has been the standard of care for patients with metastatic PDAC with marginal effects on overall survival (OS). Sebastian Krug; Department of Internal Medicine I, Martin-Luther-University Halle-Wittenberg, Halle, Germany Correspondence to Professor Patrick Michl, Department of Internal Medicine I, Martin-Luther-University Halle-Wittenberg, Halle 06120, Germany; patrick.michl{at}uk-halle.de These tumors are characterized by clinical and prognostical heterogeneity and are predominantly diagnosed in a metastatic stage. Based on their rarity, the knowledge of paraneoplastic syndromes occurring in patients with pulmonary NET such as ac … In seguito, ha sviluppato un personalissimo stile nelle caricature di personaggi famosi, rientrando nella corrente artistica definita “New Pop Realism”. (XLS). Sebastian Krug Personaloberarzt Schwerpunkte: Gastrointestinale Tumore, Neuroendokrine Tumore Telefon: 0345/ 557-2665 Fax: 0345/ 557-2253: Frank Noack Schwerpunkte: Pneumologie / Notfallmedizin Telefon: 0345/ 557-2018 Fax: 0345/ 557-5822 : apl. All Titles Year Calendar Place Author. A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Color-coded dupl... Pancreatic ductal adenocarcinomas belong to the most aggressive solid malignancies. The growth factor Ang2 (Angiopoietin2), which is invol... Join ResearchGate to find the people and research you need to help your work. Telefon: (0345) 557 2665Telefax: (0345) 557 2253E-Mail: ute.lange(at)uk-halle.de, Sekretariat Pneumologie:Sabine Herbaczowski, Telefon: (0345) 557 3238Telefax: (0345) 557 2253E-Mail: sabine.herbaczowski(at)uk-halle.de, Hausanschrift:Universitätsklinikum Halle (Saale)Universitätsklinik und Poliklinik für Innere Medizin IErnst-Grube-Straße 4006120 Halle (Saale), Kontakt für Einweiser:Belegmanager:Montag - Freitag 7:00 - 15:30 UhrTelefon: (0345) 557 5530, 24h-Facharzthotline für Einweiser:(0345) 557 2612, Umfrage zur Nutzung unserer Internetseite, Sehr geehrte/r Besucher/in unseres Internetauftrittes, Due to our privacy policy, only current members can send messages to people on ResearchGate. Manuscripts / Autographs. Objective: The COVID-19 pandemic challenges health care systems worldwide. His interest in illustration began early, at the age of three, when he became obsessed with drawing the character of Donald Duck as he had seen in Disney movies and cartoons. ], New developments in pancreatic cancer treatment, Successful selective internal radiotherapy (SIRT) in a patient with a malignant solid pseudopapillary pancreatic neoplasm (SPN), CUX1 vermittelt Progression in neuroendokrinen Tumoren, Knock-down of Pdcd4 stimulates angiogenesis via up-regulation of angiopoietin-2, Surface Maps of LO Pegasi May-July 2011 Generated via BVRI Light Curve Inversion, CUX1 Mediates Progression of Neuroendocrine Tumors, Knock-down of Pdcd4 Impairs Angiogenesis Via Up-regulation of Angiopoietin-2, Division of Epidemiology and Biostatistics, Department of Surgical and Perioperative Sciences, Institute of Pathology and Neuropathology. Prof.Dr. Orientation. sha... Pdcd4 (programmed cell death 4) is a new tumour suppressor. Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube. We report the case of a 43 years old... Myeloid cells including tumor-associated macrophages (TAM) and myeloid-derived suppressor cells (MDSC) are known as important mediators of tumor progression in solid tumors such as pancreatic cancer. Molecular pathways that determine the malignant phenotype are still insufficiently understood and have limited the use of effective combinat... Background Temozolomide as mono- or combination therapy has been suggested to be a promising alternative. Halle Reports. Previous... Chromogranin A (CgA) is a well-established marker for diagnosis and follow up of patients with gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN). Background Organizzazione insieme a Jean-François Goubet (Université d’Artois) e Oliver-Pierre Rudolph (Universität Halle) Humboldt-Kolleg: Husserl und die klassische deutsche Philosophie (Parma, 12-14 marzo 2012). During the last decade, seve... Introduction:
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